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"Nonalcoholic steatohepatitis" information

LiverAtlas Disease IDHuLDi00063
NameNonalcoholic steatohepatitis
DescriptionIt is not clear how many people have NASH because it causes no symptoms. However, NASH is diagnosed in about 7 to 9 percent of people in the United States who have a liver biopsy. Most people are between the ages of 40 and 60 years, although the condition can also occur in children over the age of 10 years. NASH is seen more often in women than in men.The cause of NASH is not clear, although research is ongoing in an attempt to find effective treatments. At the present time, treatment of NASH focuses on controlling some of the medical conditions associated with it (such as diabetes and obesity) and monitoring for progression. Xref: URL
DefinitionNonalcoholic steatohepatitis (NASH) is a condition that causes inflammation and accumulation of fat and fibrous tissue in the liver (figure 1). Although a similar condition can occur in people who abuse alcohol, NASH occurs in those who do drink little to no alcohol. The exact cause of NASH is unknown. However, it is seen more frequently in people with certain medical conditions such as diabetes, obesity, and insulin resistance. Xref: URL
SynonymNASHEXACT Xref: A Comprehensive Medical and Pharmaceutical Dictionary, 2011
NASHEXACT Xref: Clinical Hepatology, 2004:Page 621
XrefClinical Hepatology,2004.Page 570
Genetics RelationGene/Protein/Pathway