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Gene basic information

LiverAtlas Gene ID

HuLG000022

Entrez Gene ID

29

Official Gene Symbol

ABR

Synonyms

FLJ45954|MDB

Gene name

active BCR-related gene

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.3

Protein products

Active breakpoint cluster region-related protein

cDNA FLJ42556 fis, clone BRACE3005760, highly similar to Active breakpoint cluster region-related protein

Active BCR-related

cDNA FLJ44934 fis, clone BRAMY3017920, highly similar to Active breakpoint cluster region-related protein

Database cross reference

HGNC:81
MIM:600365
Ensembl:ENSG00000159842
HPRD:02649
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

 

Ontology annotation

GO ID

GO annotation

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO:0005096

GTPase activator activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005829

cytosol

GO:0006915

apoptosis

GO:0007264

small GTPase mediated signal transduction

GO:0008624

induction of apoptosis by extracellular signals

GO:0035023

regulation of Rho protein signal transduction

GO:0043547

positive regulation of GTPase activity

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051056

regulation of small GTPase mediated signal transduction