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Gene basic information

LiverAtlas Gene ID

HuLG000030

Entrez Gene ID

37

Official Gene Symbol

ACADVL

Synonyms

ACAD6|LCACD|VLCAD

Gene name

acyl-CoA dehydrogenase, very long chain

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.1

Known cancer genes

Yes

Protein products

Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

Acyl-Coenzyme A dehydrogenase, very long chain, isoform CRA e

Related liver disease name

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:92
MIM:609575
Ensembl:ENSG00000072778
HPRD:01940
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000062

fatty-acyl-CoA binding

GO:0001659

temperature homeostasis

GO:0003995

acyl-CoA dehydrogenase activity

GO:0004466

long-chain-acyl-CoA dehydrogenase activity

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005759

mitochondrial matrix

GO:0006631

fatty acid metabolic process

GO:0006635

fatty acid beta-oxidation

GO:0015980

energy derivation by oxidation of organic compounds

GO:0016020

membrane

GO:0017099

very long-chain-acyl-CoA dehydrogenase activity

GO:0033539

fatty acid beta-oxidation using acyl-CoA dehydrogenase

GO:0042645

mitochondrial nucleoid

GO:0042760

very long-chain fatty acid catabolic process

GO:0044255

cellular lipid metabolic process

GO:0045717

negative regulation of fatty acid biosynthetic process

GO:0046322

negative regulation of fatty acid oxidation

GO:0050660

flavin adenine dinucleotide binding

GO:0090181

regulation of cholesterol metabolic process