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Gene basic information

LiverAtlas Gene ID

HuLG000035

Entrez Gene ID

43

Official Gene Symbol

ACHE

Synonyms

ARACHE|NNACHE|YT

Gene name

acetylcholinesterase

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q22

Known cancer genes

Yes

Protein products

Acetylcholinesterase

Uncharacterized protein

Acetylcholinesterase (Yt blood group), isoform CRA a

N-terminal extended acetylcholinesterase

Database cross reference

HGNC:108
MIM:100740
Ensembl:ENSG00000087085
HPRD:00010
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

 

Ontology annotation

GO ID

GO annotation

GO:0001507

acetylcholine catabolic process in synaptic cleft

GO:0001540

beta-amyloid binding

GO:0001919

regulation of receptor recycling

GO:0002076

osteoblast development

GO:0003990

acetylcholinesterase activity

GO:0004091

carboxylesterase activity

GO:0004104

cholinesterase activity

GO:0005515

protein binding

GO:0005518

collagen binding

GO:0005576

extracellular region

GO:0005605

basal lamina

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0005788

endoplasmic reticulum lumen

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0006260

DNA replication

GO:0006581

acetylcholine catabolic process

GO:0007155

cell adhesion

GO:0007268

synaptic transmission

GO:0007271

synaptic transmission, cholinergic

GO:0007399

nervous system development

GO:0007416

synapse assembly

GO:0007517

muscle organ development

GO:0008283

cell proliferation

GO:0009611

response to wounding

GO:0009986

cell surface

GO:0016020

membrane

GO:0016787

hydrolase activity

GO:0017171

serine hydrolase activity

GO:0019695

choline metabolic process

GO:0030054

cell junction

GO:0030424

axon

GO:0030425

dendrite

GO:0031225

anchored to membrane

GO:0031594

neuromuscular junction

GO:0031623

receptor internalization

GO:0032223

negative regulation of synaptic transmission, cholinergic

GO:0042136

neurotransmitter biosynthetic process

GO:0042166

acetylcholine binding

GO:0042734

presynaptic membrane

GO:0042803

protein homodimerization activity

GO:0042982

amyloid precursor protein metabolic process

GO:0043237

laminin-1 binding

GO:0043621

protein self-association

GO:0045202

synapse

GO:0045211

postsynaptic membrane

GO:0045212

neurotransmitter receptor biosynthetic process

GO:0048471

perinuclear region of cytoplasm

GO:0048814

regulation of dendrite morphogenesis

GO:0050714

positive regulation of protein secretion

GO:0050770

regulation of axonogenesis

GO:0050804

regulation of synaptic transmission

GO:0051262

protein tetramerization

GO:0060041

retina development in camera-type eye