Gene basic information
| LiverAtlas Gene ID |
HuLG000036 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ACLY |
|
Synonyms |
ACL|ATPCL|CLATP |
|
Gene name |
ATP citrate lyase |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17q21.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:115
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0003878 |
ATP citrate synthase activity |
|
GO:0004775 |
succinate-CoA ligase (ADP-forming) activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005829 |
cytosol |
|
GO:0006101 |
citrate metabolic process |
|
GO:0006112 |
energy reserve metabolic process |
|
GO:0006200 |
ATP catabolic process |
|
GO:0008610 |
lipid biosynthetic process |
|
GO:0008815 |
citrate (pro-3S)-lyase activity |
|
GO:0009346 |
citrate lyase complex |
|
GO:0015936 |
coenzyme A metabolic process |
|
GO:0016740 |
transferase activity |
|
GO:0016874 |
ligase activity |
|
GO:0019432 |
triglyceride biosynthetic process |
|
GO:0031325 |
positive regulation of cellular metabolic process |
|
GO:0035338 |
long-chain fatty-acyl-CoA biosynthetic process |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0044262 |
cellular carbohydrate metabolic process |
|
GO:0046872 |
metal ion binding |
