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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000037

Entrez Gene ID

48

Official Gene Symbol

ACO1

Synonyms

ACONS|IREB1|IREBP|IREBP1|IRP1

Gene name

aconitase 1, soluble

Gene Type

protein-coding

Chromosome

9

Genomics Location

9p22-q32|9p21.1

Protein products

Cytoplasmic aconitate hydratase

Aconitase

Mucin

Aconitase 1, soluble

Iron regulatory protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:117
MIM:100880
Ensembl:ENSG00000122729
HPRD:00013
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003723

RNA binding

GO:0003994

aconitate hydratase activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005783

endoplasmic reticulum

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0006099

tricarboxylic acid cycle

GO:0006101

citrate metabolic process

GO:0006417

regulation of translation

GO:0006879

cellular iron ion homeostasis

GO:0008152

metabolic process

GO:0009791

post-embryonic development

GO:0010040

response to iron(II) ion

GO:0010468

regulation of gene expression

GO:0016829

lyase activity

GO:0030350

iron-responsive element binding

GO:0046872

metal ion binding

GO:0050892

intestinal absorption

GO:0051539

4 iron, 4 sulfur cluster binding

GO:0052632

citrate hydro-lyase (cis-aconitate-forming) activity

GO:0052633

isocitrate hydro-lyase (cis-aconitate-forming) activity