Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000039

Entrez Gene ID

50

Official Gene Symbol

ACO2

Synonyms

ACONM|MGC20605|MGC33908

Gene name

aconitase 2, mitochondrial

Gene Type

protein-coding

Chromosome

22

Genomics Location

22q11.2-q13.31|22q13.2

Known cancer genes

Yes

Protein products

Aconitase 2, mitochondrial

Aconitate hydratase, mitochondrial

Aconitase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:118
MIM:100850
Ensembl:ENSG00000100412
HPRD:00012
RefSeq Genomic nucleotide accession:AC_000065
RefSeq Genomic nucleotide gi:89161202

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003994

aconitate hydratase activity

GO:0005506

iron ion binding

GO:0005634

nucleus

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0006091

generation of precursor metabolites and energy

GO:0006099

tricarboxylic acid cycle

GO:0006101

citrate metabolic process

GO:0006102

isocitrate metabolic process

GO:0008152

metabolic process

GO:0016829

lyase activity

GO:0046872

metal ion binding

GO:0051538

3 iron, 4 sulfur cluster binding

GO:0051539

4 iron, 4 sulfur cluster binding

GO:0052632

citrate hydro-lyase (cis-aconitate-forming) activity

GO:0052633

isocitrate hydro-lyase (cis-aconitate-forming) activity