Gene basic information
LiverAtlas Gene ID |
HuLG000039 |
Entrez Gene ID |
|
Official Gene Symbol |
ACO2 |
Synonyms |
ACONM|MGC20605|MGC33908 |
Gene name |
aconitase 2, mitochondrial |
Gene Type |
protein-coding |
Chromosome |
22 |
Genomics Location |
22q11.2-q13.31|22q13.2 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:118
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003994 |
aconitate hydratase activity |
GO:0005506 |
iron ion binding |
GO:0005634 |
nucleus |
GO:0005739 |
mitochondrion |
GO:0005759 |
mitochondrial matrix |
GO:0006091 |
generation of precursor metabolites and energy |
GO:0006099 |
tricarboxylic acid cycle |
GO:0006101 |
citrate metabolic process |
GO:0006102 |
isocitrate metabolic process |
GO:0008152 |
metabolic process |
GO:0016829 |
lyase activity |
GO:0046872 |
metal ion binding |
GO:0051538 |
3 iron, 4 sulfur cluster binding |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
GO:0052632 |
citrate hydro-lyase (cis-aconitate-forming) activity |
GO:0052633 |
isocitrate hydro-lyase (cis-aconitate-forming) activity |