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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG002118

Entrez Gene ID

3105

Official Gene Symbol

HLA-A

Synonyms

FLJ26655|HLAA

Gene name

major histocompatibility complex, class I, A

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Known cancer genes

Yes

Protein products

HLA class I histocompatibility antigen, A-1 alpha chain

HLA class I histocompatibility antigen, A-3 alpha chain

HLA class I histocompatibility antigen, A-11 alpha chain

HLA class I histocompatibility antigen, A-23 alpha chain

HLA class I histocompatibility antigen, A-30 alpha chain

HLA class I histocompatibility antigen, A-33 alpha chain

HLA class I histocompatibility antigen, A-36 alpha chain

HLA class I histocompatibility antigen, A-80 alpha chain

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

cDNA, FLJ93604, highly similar to Homo sapiens major histocompatibility complex, class I, A (HLA-A),mRNA

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

HLA-A protein

HLA-A protein

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

Major histocompatibility complex, class I, A

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

MHC class I antigen

Leucocyte antigen A

MHC class I antigen heavy chain

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Biliary cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Autoimmune hepatitis

Database cross reference

HGNC:4931
MIM:142800
Ensembl:ENSG00000206503
HPRD:00826
RefSeq Genomic nucleotide accession:NC_000006
RefSeq Genomic nucleotide gi:224589818

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0002474

antigen processing and presentation of peptide antigen via MHC class I

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006955

immune response

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016032

viral reproduction

GO:0019221

cytokine-mediated signaling pathway

GO:0019882

antigen processing and presentation

GO:0031901

early endosome membrane

GO:0032393

MHC class I receptor activity

GO:0042612

MHC class I protein complex

GO:0044419

interspecies interaction between organisms

GO:0050690

regulation of defense response to virus by virus

GO:0050776

regulation of immune response

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway