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Gene basic information

LiverAtlas Gene ID

HuLG019798

Entrez Gene ID

4880

Official Gene Symbol

NPPC

Synonyms

CNP

Gene name

natriuretic_peptide_C

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q24-qter

Protein products

Programmed cell death 1 ligand 1ligand 1; AltName: Full=B7 homolog 1; Short=B7-H1; AltName: CD_antigen=CD274; Flags: Pr

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:7941
MIM:600296
Ensembl:ENSG00000163273
HPRD:08975
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198
http://www.ncbi.nlm.nih.gov/nuccore/AC_000134?report=genbank
RefSeq Genomic nucleotide gi:224589811

 

Ontology annotation

GO ID

GO annotation

GO:0001503

ossification

GO:0001666

response to hypoxia

GO:0003418

growth plate cartilage chondrocyte differentiation

GO:0003419

growth plate cartilage chondrocyte proliferation

GO:0005102

receptor binding

GO:0005179

hormone activity

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006182

cGMP biosynthetic process

GO:0007168

receptor guanylyl cyclase signaling pathway

GO:0008217

regulation of blood pressure

GO:0008285

negative regulation of cell proliferation

GO:0009791

post-embryonic development

GO:0019229

regulation of vasoconstriction

GO:0030828

positive regulation of cGMP biosynthetic process

GO:0040014

regulation of multicellular organism growth

GO:0042493

response to drug

GO:0042803

protein homodimerization activity

GO:0045471

response to ethanol

GO:0045669

positive regulation of osteoblast differentiation

GO:0045909

positive regulation of vasodilation

GO:0048513

organ development

GO:0048660

regulation of smooth muscle cell proliferation

GO:0050880

regulation of blood vessel size

GO:0051053

negative regulation of DNA metabolic process

GO:0051428

peptide hormone receptor binding