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Protein basic information

LiverAtlas Protein ID

HuLPr11242

Uniprot ID

B7UEF2_HUMAN

Uniprot Acc

B7UEF2;

Protein name

Abl2 isoform 1ASCTS

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 SH2 domain.||SIMILARITY:Contains 1 SH3 domain.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

v-abl Abelson murine leukemia viral oncogene homolog 2

Protein sequence

MVLGTVLLPPNTYGRDQDTSLCCLCTEASESALPDLTEAL HRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVAL YDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQ GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLING SFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV TAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTV YGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKY SLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLG VCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLY MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVAD FGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKS DVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRME QPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH DSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLK KQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPA LPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRN APTPPKRSSSFREMENQPHKKYELTGLPEQDRMAMTLPR NCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAA PSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGV AGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAA PVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFK LLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSI CSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAG RPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAA EKISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQ LLDYCSGYVDCIPQTRNKFAFREA

Database cross reference

RefSeq Protein accession:NP_001129472
RefSeq Protein gi:209862772

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004715;F:non-membrane spanning protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro.