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Protein basic information

LiverAtlas Protein ID

HuLPr11243

Uniprot ID

B7UEF3_HUMAN

Uniprot Acc

B7UEF3;

Protein name

Abl2 isoform 1BLCTS

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 SH2 domain.||SIMILARITY:Contains 1 SH3 domain.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

v-abl Abelson murine leukemia viral oncogene homolog 2

Protein sequence

MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGR TTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRP YGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDF VASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWV PSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFL VRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAE SRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGV SPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLT VAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCT LEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMAT QISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVW AFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPE GCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSS ISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQV ENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPR KQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPT PPKRSSSFREMENQPHKKYELTGLPEQDRMAMTLPRNCQ RSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSR ERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGV AAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVL PTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLS EHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSD PTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPV MPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKI SADKISKEALLECADLLSSALTEP

Database cross reference

RefSeq Protein accession:NP_001129472
RefSeq Protein gi:209862772

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004715;F:non-membrane spanning protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro.