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Protein basic information

LiverAtlas Protein ID

HuLPr11244

Uniprot ID

B7UEF4_HUMAN

Uniprot Acc

B7UEF4;

Protein name

Abl2 isoform 1BSCTL

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 SH2 domain.||SIMILARITY:Contains 1 SH3 domain.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

v-abl Abelson murine leukemia viral oncogene homolog 2

Protein sequence

MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGR TTETGFNIFTQHEALHRPYGCDVEPQALNEAIRWSSKEN LLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGY NQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPV SRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRV YHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLV TTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLG GGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYL RECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAA RNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKW TAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGID LSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADR PSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY LPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLA PGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTR DRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYEL TGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQ RNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGL RAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLP RNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESA APSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVG VAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKA APVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKF KLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPS ICSDPTEEPTALTAGQSTSETQEG

Database cross reference

RefSeq Protein accession:NP_001129472
RefSeq Protein gi:209862772

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004715;F:non-membrane spanning protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro.