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Protein basic information

LiverAtlas Protein ID

HuLPr11245

Uniprot ID

B7UEF5_HUMAN

Uniprot Acc

B7UEF5;

Protein name

Abl2 isoform 1BSCTS

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 SH2 domain.||SIMILARITY:Contains 1 SH3 domain.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

v-abl Abelson murine leukemia viral oncogene homolog 2

Protein sequence

MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGR TTETGFNIFTQHEALHRPYGCDVEPQALNEAIRWSSKEN LLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGY NQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPV SRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRV YHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLV TTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLG GGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYL RECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAA RNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKW TAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGID LSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADR PSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY LPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLA PGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTR DRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYEL TGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVD RANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPS GDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVP EDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPA DVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCA PPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGG KKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANG TAGTKVALRKTKQAAEKISADKISKEALLECADLLSSAL TEPVPNSQLVDTGHQLLDYCSGYV

Database cross reference

RefSeq Protein accession:NP_001129472
RefSeq Protein gi:209862772

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004715;F:non-membrane spanning protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0006468;P:protein phosphorylation;IEA:InterPro.