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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr18442

Uniprot ID

DISP2_HUMAN

Uniprot Acc

A7MBM2;Q6AHW3;Q9C0C1;

Protein name

Protein dispatched homolog 2

Comment

SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (Potential).||SIMILARITY:Belongs to the dispatched family.||SIMILARITY:Contains 1 SSD (sterol-sensing) domain.||SEQUENCE CAUTION:Sequence=BAB21833.2; Type=Erroneous termination; Positions=100; Note=Translated as Gln;

Subcellular localization

Membrane;Multi-pass membrane protein(Potential).

Gene name

dispatched homolog 2 (Drosophila)

Protein sequence

MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDS TQTKAVPPEASPERSCSLHSCPLEDPSSSSGPPPTTSTL QPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALC SHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQM PKSYSQLIAEWPVAVLMLCLAVIFLCTLAGLLGARLPDF SKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPD LELNSSSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQ ENFFCGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQ DQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSS CLDTTQADAARTLALLRTCALYYHSGALVPSCLGPGQNK SPRCAQVPTKCSQSSAIYQLLHFLLDRDFLSPQTTDYQV PSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSV TGMDLGLKQELLRHFLVQDTVYPLLALVAIFFGMALYLR SLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAA LLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTM HHFGYLLLVSGLTTSAAFYASYLSRLPAVRCLALFMGTA VLVHLALTLVWLPASAVLHERYLARGCARRARGRWEGSA PRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFR YIWICWFAALAAGGAYIAGVSPRLRLPTLPPPGGQVFRP SHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLPV DTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRAR NQSFFDTLQEGWPTLCFVETLQRWMESPSCARLGPDLCC GHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHG SLAALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGM APPGLRRGWFTSRLELYSLQHSLSTEPAVVLGLALALAF ATLLLGTWNVPLSLFSVAAVAGTV

Database cross reference

RefSeq Protein accession:NP_277045
RefSeq Protein gi:25121980

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-P

GO:0007224;P:smoothened signaling pathway;NAS:UniProtKB.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr18442

PHOSPHORYLATION

1173

S

PhosphoSitePlus

480104

LTP

HTP

N

HuLPr18442

PHOSPHORYLATION

1175

S

PhosphoSitePlus

478729

LTP

N

HuLPr18442

PHOSPHORYLATION

1151

S

PhosphoSitePlus

5207652

LTP

N

HuLPr18442

PHOSPHORYLATION

428

Y

PhosphoSitePlus

974778

LTP

N

HuLPr18442

PHOSPHORYLATION

1393

S

PhosphoSitePlus

4959458

LTP

N

Pathway

Pathway name

Hedgehog