Protein basic information
| LiverAtlas Protein ID |
HuLPr24563 |
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Uniprot ID |
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Uniprot Acc |
P69892;A8MZE0;P02096;P62027;Q14491;Q68NH9;Q96FH6;Q96FH7; |
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Protein name |
Hemoglobin subunit gamma-2 |
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Comment |
FUNCTION:Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.||SUBUNIT:Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F).||TISSUE SPECIFICITY:Red blood cells.||DEVELOPMENTAL STAGE:Expressed until four or five weeks after birth.||PTM:Acetylation of Gly-2 converts Hb F to the minor Hb F1.||SIMILARITY:Belongs to the globin family.||SEQUENCE CAUTION:Sequence=AAB50159.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;||WEB RESOURCE:Name=HbVar; Note=Human hemoglobin variants and thalassemias; URL="http://globin.bx.psu.edu/cgi-bin/hbvar/query vars3?mode=directlink&gene=HBG2"; |
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Gene name |
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Protein sequence
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MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQ RFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHL DDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH FGKEFTPEVQASWQKMVTGVASALSSRYH |
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Database cross reference |
RefSeq Protein accession:NP_000175
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Human Fetal Liver;Chinese Liver;French Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005833;C:hemoglobin complex;IEA:InterPro. |
|
GO-F |
GO:0020037;F:heme binding;IEA:InterPro. GO:0019825;F:oxygen binding;IEA:InterPro. GO:0005344;F:oxygen transporter activity;IEA:UniProtKB-KW. |
|
GO-P |
GO:0007596;P:blood coagulation;TAS:Reactome. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr24563 |
PHOSPHORYLATION |
36 |
Y |
Phospho-ELM |
HTP |
N |
 
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|
|
HuLPr24563 |
PHOSPHORYLATION |
36 |
Y |
PhosphoSitePlus |
LTP |
N |
|
Pathway
| Pathway name |
