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Protein basic information

LiverAtlas Protein ID

HuLPr44207

Uniprot ID

RDH13_HUMAN

Uniprot Acc

Q8NBN7;Q6UX79;Q96G88;

Protein name

Retinol dehydrogenase 13

Comment

FUNCTION:Does not exhibit retinol dehydrogenase (RDH) activity in vitro.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NBN7-1; Sequence=Displayed; Name=2; IsoId=Q8NBN7-2; Sequence=VSP 040383;||TISSUE SPECIFICITY:Expressed mostly in eye, pancreas, placenta and lung. In the retina, detected in the inner segment of the photoreceptor cells. Weak signals were observed in a small population of inner nuclear neurons and the inner plexiform layer.||SIMILARITY:Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Gene name

retinol dehydrogenase 13 (all-trans/9-cis)

Protein sequence

MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKT VIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAA KDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERV DILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLL LDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNT KAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVART ELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYL AVAEELADVSGKYFDGLKQKAPAPEAEDEEVARRLWAES ARLVGLEAPSVREQPLPR

Database cross reference

RefSeq Protein accession:NP_001139443
RefSeq Protein gi:225579078

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005488;F:binding;IEA:InterPro. GO:0016491;F:oxidoreductase activity;IEA:UniProtKB-KW.

Pathway

Pathway name

2-Hydroxyglutric_Aciduria_(D_And_L_Form)