"Primary biliary cirrhosis" information
| LiverAtlas Disease ID | HuLDi00112 | ||
| Name | Primary biliary cirrhosis | ||
| Description | Xref: | ||
| Definition | 1.An autoimmune inflammatory disorder characterized by destruction of the small intrahepatic bile ducts. It affects predominantly females and it may lead to cirrhosis and liver failure. Patients have antimitochondrial and antinuclear antibodies in the peripheral blood. | Xref: UMLS2011AA:C0008312 | |
| 2.A form of biliary cirrhosis in which small intrahepatic ducts are destroyed while the major intra and extra hepatic ducts remain patent; most patients are middle aged females and have circulating antimitochondrial antibodies. | Xref: UMLS2011AA:C0008312 | ||
| Synonym | Biliary Cirrhosis, Primary | EXACT | Xref: MeSH2011_6_17:D008105 |
| PBC | EXACT | Xref: Clinical Hepatology, 2004:Page 437 | |
| primary biliary cirrhosis | EXACT | Xref: CSP2005:4000-0298, HumanDO2011_6_18:DOID:12236 | |
| Primary biliary cirrhosis | EXACT | Xref: UMLS2011AA:C0008312 | |
| Primary Biliary Cirrhosis | EXACT | Xref: Schiff's Diseases of the LIVER, 10ed:Chapter 24, MeSH2011_6_17:D008105 | |
| Xref | Clinical Hepatology,2004.Page 483 | ||
| HumanDO2011_6_18:DOID:12236 | |||
| MeSH2011_6_17:D008105 | |||
| Genetics Relation | Gene/Protein/Pathway | ||
| Gene:ALB | Gene:ALPP | Gene:AIRE | Gene:FAS | Gene:FAS | Gene:ASGR2 | Gene:BCL2 |
| more... | |||
