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"D2G000422Ge00008802" information

LiverAtlasDisease Name Alcoholic liver cirrhosis
Gene/Protein/Pathway Gene:ADH1C
SourceGAD:143935
Phenotypealcohol abuse cirrhosis, alcoholic pancreatitis, chronic
Detection MethodText mining and Manually revised
AssociationYes
Change TypeUncategorized
ConclusionIn the Polish population examined, the ADH3*1 allele and the ADH3*1/*1 genotype are conducive to the development of alcoholism, alcohol liver Cirrhosis and alcohol chronic pancreatitis. However, the ADH2*2 allele is likely to protect against these conditions. Genetic polymorphism of ALDH2 shows no correlation with alcohol addiction or alcohol cirrhosis and alcohol chronic pancreatitis. The ADH3*1 allele and the ADH3*1/*1 genotype are conducive to alcohol abuse starting at a younger age.
Conclusion1
ReferenceLt00000253
Confidence