"D2G000252Ge00488600" information
LiverAtlasDisease Name | Liver fibrosis and liver cirrhosis caused by hepatitis C infection | ||||
Gene/Protein/Pathway | Gene:TLR4 | ||||
Source | GAD:560381 | ||||
Phenotype | Chronic Hepatitis C | ||||
Detection Method | Text mining and Manually revised | ||||
Association | Unassigned | ||||
Change Type | Uncategorized | ||||
Conclusion | Collectively, these results demonstrate the differential effects of donor and recipient TLR4 signaling in human liver transplantation. Donor TLR4 contributed to sterile injury following cold preservation and the recipient TLR4 genotype was linked with poor allograft survival among HCV infected recipients.;Homozygous TLR2 Arg753Gln polymorphism is associated with allograft failure and mortality after liver transplantation for chronic HCV.Conclusion1 | ||||
Reference | Lt00000354 | ||||
Confidence |