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"D2G002092Ge00483300" information

LiverAtlasDisease Name Liver fibrosis and liver cirrhosis caused by hepatitis C infection
Gene/Protein/Pathway Gene:TGFB1
SourceGAD:135979
PhenotypeHCV-induced liver fibrosis
Detection MethodText mining and Manually revised
AssociationUnassigned
Change TypeUncategorized
ConclusionOur results indicate that the heterozygous ArgPro of codon 25 predicts significantly faster fibrotic progression of chronic hepatitis C than the homozygous (25)ArgArg genotype. The homozygous LeuLeu genotype of codon 10 showed a slow progression of fibrosis.
Conclusion1
ReferenceLt00000158
Confidence