Gene basic information
LiverAtlas Gene ID |
HuLG000005 |
Entrez Gene ID |
|
Official Gene Symbol |
SERPINA3 |
Synonyms |
AACT|ACT|GIG25|MGC88254 |
Gene name |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
Gene Type |
protein-coding |
Chromosome |
14 |
Genomics Location |
14q32.1 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:16
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003677 |
DNA binding |
GO:0004867 |
serine-type endopeptidase inhibitor activity |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0006953 |
acute-phase response |
GO:0006954 |
inflammatory response |
GO:0010951 |
negative regulation of endopeptidase activity |
GO:0019216 |
regulation of lipid metabolic process |
GO:0030162 |
regulation of proteolysis |
GO:0030277 |
maintenance of gastrointestinal epithelium |
GO:0030414 |
peptidase inhibitor activity |