Gene basic information
| LiverAtlas Gene ID |
HuLG000012 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ABCA1 |
|
Synonyms |
ABCN1|ABC1|CERP|FLJ14958|HDLDT1|MGC164864|MGC165011|TGD |
|
Gene name |
ATP-binding cassette, sub-family A (ABC1), member 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
9 |
|
Genomics Location |
9q31.1 |
|
Known cancer genes |
Yes |
|
Protein products |
ATP-binding cassette sub-family A member 1 ATP-binding cassette, sub-family A (ABC1), member 1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:29
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0002790 |
peptide secretion |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005543 |
phospholipid binding |
|
GO:0005548 |
phospholipid transporter activity |
|
GO:0005624 |
membrane fraction |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006497 |
protein lipidation |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006810 |
transport |
|
GO:0006820 |
anion transport |
|
GO:0006911 |
phagocytosis, engulfment |
|
GO:0007040 |
lysosome organization |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0008202 |
steroid metabolic process |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008509 |
anion transmembrane transporter activity |
|
GO:0010745 |
negative regulation of macrophage derived foam cell differentiation |
|
GO:0010875 |
positive regulation of cholesterol efflux |
|
GO:0010887 |
negative regulation of cholesterol storage |
|
GO:0015485 |
cholesterol binding |
|
GO:0016197 |
endosome transport |
|
GO:0016887 |
ATPase activity |
|
GO:0017127 |
cholesterol transporter activity |
|
GO:0030139 |
endocytic vesicle |
|
GO:0030349 |
syntaxin-13 binding |
|
GO:0030819 |
positive regulation of cAMP biosynthetic process |
|
GO:0031267 |
small GTPase binding |
|
GO:0032367 |
intracellular cholesterol transport |
|
GO:0032488 |
Cdc42 protein signal transduction |
|
GO:0033344 |
cholesterol efflux |
|
GO:0033700 |
phospholipid efflux |
|
GO:0034185 |
apolipoprotein binding |
|
GO:0034186 |
apolipoprotein A-I binding |
|
GO:0034188 |
apolipoprotein A-I receptor activity |
|
GO:0034380 |
high-density lipoprotein particle assembly |
|
GO:0042157 |
lipoprotein metabolic process |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0043691 |
reverse cholesterol transport |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0045121 |
membrane raft |
|
GO:0045332 |
phospholipid translocation |
|
GO:0045335 |
phagocytic vesicle |
|
GO:0050702 |
interleukin-1 beta secretion |
|
GO:0055091 |
phospholipid homeostasis |
|
GO:0060155 |
platelet dense granule organization |
|
GO:0071222 |
cellular response to lipopolysaccharide |
|
GO:0071300 |
cellular response to retinoic acid |
