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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000024

Entrez Gene ID

31

Official Gene Symbol

ACACA

Synonyms

ACAC|ACC|ACC1|ACCA

Gene name

acetyl-CoA carboxylase alpha

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q21

Known cancer genes

Yes

Protein products

Acetyl-CoA carboxylase 1

Acetyl-Coenzyme A carboxylase alpha

Acetyl-CoA carboxylase 1

ACACA protein

Related liver disease name

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:84
MIM:200350
Ensembl:ENSG00000132142
HPRD:01938
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001894

tissue homeostasis

GO:0003989

acetyl-CoA carboxylase activity

GO:0004075

biotin carboxylase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005829

cytosol

GO:0006084

acetyl-CoA metabolic process

GO:0006112

energy reserve metabolic process

GO:0006633

fatty acid biosynthetic process

GO:0009374

biotin binding

GO:0014070

response to organic cyclic compound

GO:0016874

ligase activity

GO:0019432

triglyceride biosynthetic process

GO:0031325

positive regulation of cellular metabolic process

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

GO:0042493

response to drug

GO:0044255

cellular lipid metabolic process

GO:0044268

multicellular organismal protein metabolic process

GO:0046872

metal ion binding

GO:0051289

protein homotetramerization

GO:0055088

lipid homeostasis