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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000025

Entrez Gene ID

32

Official Gene Symbol

ACACB

Synonyms

ACC2|ACCB|HACC275

Gene name

acetyl-CoA carboxylase beta

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.11

Known cancer genes

Yes

Protein products

Acetyl-CoA carboxylase 2

Related liver disease name

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:85
MIM:601557
Ensembl:ENSG00000076555
HPRD:07044
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003989

acetyl-CoA carboxylase activity

GO:0004075

biotin carboxylase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005737

cytoplasm

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0006084

acetyl-CoA metabolic process

GO:0006112

energy reserve metabolic process

GO:0006633

fatty acid biosynthetic process

GO:0006853

carnitine shuttle

GO:0012505

endomembrane system

GO:0016020

membrane

GO:0016874

ligase activity

GO:0031325

positive regulation of cellular metabolic process

GO:0044255

cellular lipid metabolic process

GO:0046320

regulation of fatty acid oxidation

GO:0046872

metal ion binding

GO:0051289

protein homotetramerization