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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000031

Entrez Gene ID

38

Official Gene Symbol

ACAT1

Synonyms

ACAT|MAT|T2|THIL

Gene name

acetyl-CoA acetyltransferase 1

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q22.3

Known cancer genes

Yes

Protein products

ACAT1 protein

Acetyl-CoA acetyltransferase, mitochondrial

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:93
MIM:607809
Ensembl:ENSG00000075239
HPRD:01946
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001889

liver development

GO:0003985

acetyl-CoA C-acetyltransferase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0007420

brain development

GO:0008415

acyltransferase activity

GO:0009083

branched chain family amino acid catabolic process

GO:0009725

response to hormone stimulus

GO:0014070

response to organic cyclic compound

GO:0016740

transferase activity

GO:0019899

enzyme binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0042594

response to starvation

GO:0042803

protein homodimerization activity

GO:0043441

acetoacetic acid biosynthetic process

GO:0044255

cellular lipid metabolic process

GO:0046872

metal ion binding

GO:0046950

cellular ketone body metabolic process

GO:0046951

ketone body biosynthetic process

GO:0046952

ketone body catabolic process

GO:0050662

coenzyme binding

GO:0051260

protein homooligomerization

GO:0060612

adipose tissue development

GO:0072229

metanephric proximal convoluted tubule development