Gene basic information
LiverAtlas Gene ID |
HuLG000037 |
Entrez Gene ID |
|
Official Gene Symbol |
ACO1 |
Synonyms |
ACONS|IREB1|IREBP|IREBP1|IRP1 |
Gene name |
aconitase 1, soluble |
Gene Type |
protein-coding |
Chromosome |
9 |
Genomics Location |
9p22-q32|9p21.1 |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:117
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003723 |
RNA binding |
GO:0003994 |
aconitate hydratase activity |
GO:0005515 |
protein binding |
GO:0005737 |
cytoplasm |
GO:0005739 |
mitochondrion |
GO:0005783 |
endoplasmic reticulum |
GO:0005794 |
Golgi apparatus |
GO:0005829 |
cytosol |
GO:0006099 |
tricarboxylic acid cycle |
GO:0006101 |
citrate metabolic process |
GO:0006417 |
regulation of translation |
GO:0006879 |
cellular iron ion homeostasis |
GO:0008152 |
metabolic process |
GO:0009791 |
post-embryonic development |
GO:0010040 |
response to iron(II) ion |
GO:0010468 |
regulation of gene expression |
GO:0016829 |
lyase activity |
GO:0030350 |
iron-responsive element binding |
GO:0046872 |
metal ion binding |
GO:0050892 |
intestinal absorption |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
GO:0052632 |
citrate hydro-lyase (cis-aconitate-forming) activity |
GO:0052633 |
isocitrate hydro-lyase (cis-aconitate-forming) activity |