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Gene basic information

LiverAtlas Gene ID

HuLG000050

Entrez Gene ID

70

Official Gene Symbol

ACTC1

Synonyms

ACTC|ASD5|CMD1R|CMH11|LVNC4

Gene name

actin, alpha, cardiac muscle 1

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q11-q14

Known cancer genes

Yes

Protein products

Actin, alpha cardiac muscle 1

cDNA FLJ32030 fis, clone NTONG2000040, highly similar to Actin, alpha cardiac

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:143
MIM:102540
Ensembl:ENSG00000159251
HPRD:00015
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0005524

ATP binding

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005884

actin filament

GO:0006200

ATP catabolic process

GO:0006915

apoptosis

GO:0016887

ATPase activity

GO:0017022

myosin binding

GO:0030017

sarcomere

GO:0030048

actin filament-based movement

GO:0030049

muscle filament sliding

GO:0030240

skeletal muscle thin filament assembly

GO:0031032

actomyosin structure organization

GO:0031674

I band

GO:0033275

actin-myosin filament sliding

GO:0042493

response to drug

GO:0042643

actomyosin, actin part

GO:0045471

response to ethanol

GO:0055003

cardiac myofibril assembly

GO:0055008

cardiac muscle tissue morphogenesis

GO:0060047

heart contraction

GO:0060048

cardiac muscle contraction