Gene basic information
| LiverAtlas Gene ID |
HuLG000058 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ACVR1 |
|
Synonyms |
ACTRI|ACVR1A|ACVRLK2|ALK2|FOP|SKR1|TSRI |
|
Gene name |
activin A receptor, type I |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q23-q24 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:171
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0001569 |
patterning of blood vessels |
|
GO:0001655 |
urogenital system development |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001702 |
gastrulation with mouth forming second |
|
GO:0001707 |
mesoderm formation |
|
GO:0001755 |
neural crest cell migration |
|
GO:0002526 |
acute inflammatory response |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
|
GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005025 |
transforming growth factor beta receptor activity, type I |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
|
GO:0007281 |
germ cell development |
|
GO:0007368 |
determination of left/right symmetry |
|
GO:0007498 |
mesoderm development |
|
GO:0007507 |
heart development |
|
GO:0009790 |
embryo development |
|
GO:0009968 |
negative regulation of signal transduction |
|
GO:0016020 |
membrane |
|
GO:0016361 |
activin receptor activity, type I |
|
GO:0030278 |
regulation of ossification |
|
GO:0030501 |
positive regulation of bone mineralization |
|
GO:0030509 |
BMP signaling pathway |
|
GO:0032926 |
negative regulation of activin receptor signaling pathway |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0045177 |
apical part of cell |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0046332 |
SMAD binding |
|
GO:0046872 |
metal ion binding |
|
GO:0048179 |
activin receptor complex |
|
GO:0048184 |
follistatin binding |
|
GO:0048185 |
activin binding |
|
GO:0048641 |
regulation of skeletal muscle tissue development |
|
GO:0050431 |
transforming growth factor beta binding |
|
GO:0051145 |
smooth muscle cell differentiation |
|
GO:0060037 |
pharyngeal system development |
|
GO:0071385 |
cellular response to glucocorticoid stimulus |
