Gene basic information
| LiverAtlas Gene ID |
HuLG000059 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ACVR1B |
|
Synonyms |
ACTRIB|ACVRLK4|ALK4|SKR2 |
|
Gene name |
activin A receptor, type IB |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q13 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ61341, highly similar to Activin receptor type 1B (EC 2.7.11.30) cDNA FLJ55393, highly similar to Activin receptor type 1B (EC 2.7.11.30) |
|
Database cross reference |
HGNC:172
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001942 |
hair follicle development |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
|
GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005024 |
transforming growth factor beta receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006917 |
induction of apoptosis |
|
GO:0007165 |
signal transduction |
|
GO:0007178 |
transmembrane receptor protein serine/threonine kinase signaling pathway |
|
GO:0007417 |
central nervous system development |
|
GO:0009790 |
embryo development |
|
GO:0009986 |
cell surface |
|
GO:0010862 |
positive regulation of pathway-restricted SMAD protein phosphorylation |
|
GO:0016020 |
membrane |
|
GO:0016361 |
activin receptor activity, type I |
|
GO:0017002 |
activin receptor activity |
|
GO:0018107 |
peptidyl-threonine phosphorylation |
|
GO:0019838 |
growth factor binding |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0032927 |
positive regulation of activin receptor signaling pathway |
|
GO:0045648 |
positive regulation of erythrocyte differentiation |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046332 |
SMAD binding |
|
GO:0046545 |
development of primary female sexual characteristics |
|
GO:0046777 |
protein autophosphorylation |
|
GO:0046872 |
metal ion binding |
|
GO:0048179 |
activin receptor complex |
|
GO:0048185 |
activin binding |
