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Gene basic information

LiverAtlas Gene ID

HuLG000060

Entrez Gene ID

92

Official Gene Symbol

ACVR2A

Synonyms

ACTRII|ACVR2

Gene name

activin A receptor, type IIA

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q22.3

Known cancer genes

Yes

Protein products

Activin receptor type-2A

Database cross reference

HGNC:173
MIM:102581
Ensembl:ENSG00000121989
HPRD:00025
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001702

gastrulation with mouth forming second

GO:0001934

positive regulation of protein phosphorylation

GO:0004675

transmembrane receptor protein serine/threonine kinase activity

GO:0004702

receptor signaling protein serine/threonine kinase activity

GO:0005024

transforming growth factor beta receptor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007178

transmembrane receptor protein serine/threonine kinase signaling pathway

GO:0007283

spermatogenesis

GO:0007368

determination of left/right symmetry

GO:0007498

mesoderm development

GO:0009952

anterior/posterior pattern formation

GO:0010033

response to organic substance

GO:0015026

coreceptor activity

GO:0016362

activin receptor activity, type II

GO:0017002

activin receptor activity

GO:0019838

growth factor binding

GO:0030501

positive regulation of bone mineralization

GO:0030509

BMP signaling pathway

GO:0030510

regulation of BMP signaling pathway

GO:0032927

positive regulation of activin receptor signaling pathway

GO:0034673

inhibin-betaglycan-ActRII complex

GO:0042713

sperm ejaculation

GO:0043084

penile erection

GO:0043621

protein self-association

GO:0045648

positive regulation of erythrocyte differentiation

GO:0045669

positive regulation of osteoblast differentiation

GO:0046872

metal ion binding

GO:0046881

positive regulation of follicle-stimulating hormone secretion

GO:0048185

activin binding

GO:0048186

inhibin beta-A binding

GO:0048187

inhibin beta-B binding

GO:0048706

embryonic skeletal system development

GO:0050999

regulation of nitric-oxide synthase activity

GO:0060011

Sertoli cell proliferation