Gene basic information
| LiverAtlas Gene ID |
HuLG000061 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ACVR2B |
|
Synonyms |
ACTRIIB|ActRNIIB|MGC116908 |
|
Gene name |
activin A receptor, type IIB |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p22 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Database cross reference |
HGNC:174
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001702 |
gastrulation with mouth forming second |
|
GO:0001822 |
kidney development |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
|
GO:0004712 |
protein serine/threonine/tyrosine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005024 |
transforming growth factor beta receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007165 |
signal transduction |
|
GO:0007178 |
transmembrane receptor protein serine/threonine kinase signaling pathway |
|
GO:0007368 |
determination of left/right symmetry |
|
GO:0007389 |
pattern specification process |
|
GO:0007498 |
mesoderm development |
|
GO:0007507 |
heart development |
|
GO:0009749 |
response to glucose stimulus |
|
GO:0009791 |
post-embryonic development |
|
GO:0009952 |
anterior/posterior pattern formation |
|
GO:0009986 |
cell surface |
|
GO:0016362 |
activin receptor activity, type II |
|
GO:0019838 |
growth factor binding |
|
GO:0030073 |
insulin secretion |
|
GO:0030324 |
lung development |
|
GO:0030501 |
positive regulation of bone mineralization |
|
GO:0030509 |
BMP signaling pathway |
|
GO:0031016 |
pancreas development |
|
GO:0032147 |
activation of protein kinase activity |
|
GO:0032927 |
positive regulation of activin receptor signaling pathway |
|
GO:0035265 |
organ growth |
|
GO:0042475 |
odontogenesis of dentine-containing tooth |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0046872 |
metal ion binding |
|
GO:0048185 |
activin binding |
|
GO:0048617 |
embryonic foregut morphogenesis |
|
GO:0048705 |
skeletal system morphogenesis |
|
GO:0060021 |
palate development |
