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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000066

Entrez Gene ID

100

Official Gene Symbol

ADA

Gene name

adenosine deaminase

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13.12

Known cancer genes

Yes

Protein products

Adenosine deaminase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Database cross reference

HGNC:186
MIM:608958
Ensembl:ENSG00000196839
HPRD:00038
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0001701

in utero embryonic development

GO:0001829

trophectodermal cell differentiation

GO:0001883

purine nucleoside binding

GO:0001889

liver development

GO:0001890

placenta development

GO:0002314

germinal center B cell differentiation

GO:0002636

positive regulation of germinal center formation

GO:0002686

negative regulation of leukocyte migration

GO:0002906

negative regulation of mature B cell apoptosis

GO:0004000

adenosine deaminase activity

GO:0005515

protein binding

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005764

lysosome

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006144

purine base metabolic process

GO:0006154

adenosine catabolic process

GO:0006157

deoxyadenosine catabolic process

GO:0007155

cell adhesion

GO:0007568

aging

GO:0008270

zinc ion binding

GO:0009117

nucleotide metabolic process

GO:0009168

purine ribonucleoside monophosphate biosynthetic process

GO:0009897

external side of plasma membrane

GO:0009986

cell surface

GO:0010460

positive regulation of heart rate

GO:0016020

membrane

GO:0016787

hydrolase activity

GO:0030054

cell junction

GO:0030890

positive regulation of B cell proliferation

GO:0031410

cytoplasmic vesicle

GO:0032261

purine nucleotide salvage

GO:0032839

dendrite cytoplasm

GO:0033089

positive regulation of T cell differentiation in thymus

GO:0033632

regulation of cell-cell adhesion mediated by integrin

GO:0042110

T cell activation

GO:0042542

response to hydrogen peroxide

GO:0043025

neuronal cell body

GO:0043066

negative regulation of apoptosis

GO:0043101

purine-containing compound salvage

GO:0045187

regulation of circadian sleep/wake cycle, sleep

GO:0045987

positive regulation of smooth muscle contraction

GO:0046061

dATP catabolic process

GO:0046101

hypoxanthine biosynthetic process

GO:0046103

inosine biosynthetic process

GO:0046111

xanthine biosynthetic process

GO:0046638

positive regulation of alpha-beta T cell differentiation

GO:0046872

metal ion binding

GO:0048286

lung alveolus development

GO:0048541

Peyer's patch development

GO:0048566

embryonic digestive tract development

GO:0050728

negative regulation of inflammatory response

GO:0050850

positive regulation of calcium-mediated signaling

GO:0050862

positive regulation of T cell receptor signaling pathway

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process

GO:0060169

negative regulation of adenosine receptor signaling pathway

GO:0060205

cytoplasmic membrane-bounded vesicle lumen

GO:0060407

negative regulation of penile erection

GO:0070244

negative regulation of thymocyte apoptosis

GO:0070256

negative regulation of mucus secretion