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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000089

Entrez Gene ID

127

Official Gene Symbol

ADH4

Synonyms

ADHN2

Gene name

alcohol dehydrogenase 4 (class II), pi polypeptide

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q21-q24|4q22

Protein products

Alcohol dehydrogenase 4

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:252
MIM:103740
Ensembl:ENSG00000198099
HPRD:00068
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

Translational level from literatures

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001523

retinoid metabolic process

GO:0003960

NADPH:quinone reductase activity

GO:0004022

alcohol dehydrogenase (NAD) activity

GO:0004024

alcohol dehydrogenase activity, zinc-dependent

GO:0004032

alditol:NADP+ 1-oxidoreductase activity

GO:0004745

retinol dehydrogenase activity

GO:0005503

all-trans retinal binding

GO:0005575

cellular component

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006066

alcohol metabolic process

GO:0006069

ethanol oxidation

GO:0006081

cellular aldehyde metabolic process

GO:0006805

xenobiotic metabolic process

GO:0008270

zinc ion binding

GO:0015630

microtubule cytoskeleton

GO:0016491

oxidoreductase activity

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

GO:0019115

benzaldehyde dehydrogenase activity

GO:0019841

retinol binding

GO:0042375

quinone cofactor metabolic process

GO:0042572

retinol metabolic process

GO:0046164

alcohol catabolic process

GO:0046872

metal ion binding

GO:0051287

NAD binding