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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000095

Entrez Gene ID

134

Official Gene Symbol

ADORA1

Synonyms

RDC7

Gene name

adenosine A1 receptor

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q32.1

Known cancer genes

Yes

Protein products

Adenosine receptor A1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:262
MIM:102775
Ensembl:ENSG00000163485
HPRD:00042
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000186

activation of MAPKK activity

GO:0001609

adenosine receptor activity, G-protein coupled

GO:0001659

temperature homeostasis

GO:0001664

G-protein-coupled receptor binding

GO:0001883

purine nucleoside binding

GO:0002087

regulation of respiratory gaseous exchange by neurological system process

GO:0002686

negative regulation of leukocyte migration

GO:0002793

positive regulation of peptide secretion

GO:0003093

regulation of glomerular filtration

GO:0004629

phospholipase C activity

GO:0004872

receptor activity

GO:0005515

protein binding

GO:0005783

endoplasmic reticulum

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006612

protein targeting to membrane

GO:0006909

phagocytosis

GO:0006954

inflammatory response

GO:0007165

signal transduction

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

GO:0007267

cell-cell signaling

GO:0007399

nervous system development

GO:0008285

negative regulation of cell proliferation

GO:0008624

induction of apoptosis by extracellular signals

GO:0012505

endomembrane system

GO:0014050

negative regulation of glutamate secretion

GO:0014069

postsynaptic density

GO:0016323

basolateral plasma membrane

GO:0030425

dendrite

GO:0030673

axolemma

GO:0031683

G-protein beta/gamma-subunit complex binding

GO:0032229

negative regulation of synaptic transmission, GABAergic

GO:0032244

positive regulation of nucleoside transport

GO:0032279

asymmetric synapse

GO:0032795

heterotrimeric G-protein binding

GO:0032900

negative regulation of neurotrophin production

GO:0035307

positive regulation of protein dephosphorylation

GO:0042323

negative regulation of circadian sleep/wake cycle, non-REM sleep

GO:0042734

presynaptic membrane

GO:0043025

neuronal cell body

GO:0043066

negative regulation of apoptosis

GO:0043195

terminal button

GO:0043268

positive regulation of potassium ion transport

GO:0045211

postsynaptic membrane

GO:0045741

positive regulation of epidermal growth factor receptor activity

GO:0045777

positive regulation of blood pressure

GO:0045822

negative regulation of heart contraction

GO:0045908

negative regulation of vasodilation

GO:0046888

negative regulation of hormone secretion

GO:0046982

protein heterodimerization activity

GO:0048167

regulation of synaptic plasticity

GO:0048786

presynaptic active zone

GO:0050728

negative regulation of inflammatory response

GO:0050890

cognition

GO:0050965

detection of temperature stimulus involved in sensory perception of pain

GO:0050995

negative regulation of lipid catabolic process

GO:0051967

negative regulation of synaptic transmission, glutamatergic

GO:0055118

negative regulation of cardiac muscle contraction

GO:0060079

regulation of excitatory postsynaptic membrane potential

GO:0060087

relaxation of vascular smooth muscle

GO:0070256

negative regulation of mucus secretion