HuLG000097

Entrez Gene ID

136

Official Gene Symbol

ADORA2B

Synonyms

ADORA2

Gene name

adenosine A2b receptor

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p12

Known cancer genes

Yes

Protein products

Adenosine receptor A2b

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:264
MIM:600446
Ensembl:ENSG00000170425
HPRD:15971
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

GO annotation

GO:0000187

activation of MAPK activity

GO:0001609

adenosine receptor activity, G-protein coupled

GO:0002882

positive regulation of chronic inflammatory response to non-antigenic stimulus

GO:0004872

receptor activity

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006968

cellular defense response

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007189

activation of adenylate cyclase activity by G-protein signaling pathway

GO:0007190

activation of adenylate cyclase activity

GO:0007254

JNK cascade

GO:0007588

excretion

GO:0008284

positive regulation of cell proliferation

GO:0008285

negative regulation of cell proliferation

GO:0009986

cell surface

GO:0010575

positive regulation vascular endothelial growth factor production

GO:0010701

positive regulation of norepinephrine secretion

GO:0010893

positive regulation of steroid biosynthetic process

GO:0030819

positive regulation of cAMP biosynthetic process

GO:0030828

positive regulation of cGMP biosynthetic process

GO:0031284

positive regulation of guanylate cyclase activity

GO:0031668

cellular response to extracellular stimulus

GO:0032722

positive regulation of chemokine production

GO:0032755

positive regulation of interleukin-6 production

GO:0032966

negative regulation of collagen biosynthetic process

GO:0043306

positive regulation of mast cell degranulation

GO:0045765

regulation of angiogenesis

GO:0045909

positive regulation of vasodilation

GO:0060087

relaxation of vascular smooth muscle