Gene basic information
| LiverAtlas Gene ID |
HuLG000104 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ADRA1A |
|
Synonyms |
ADRA1C|ADRA1L1|ALPHA1AAR |
|
Gene name |
adrenergic, alpha-1A-, receptor |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8p21.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:277
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0004930 |
G-protein coupled receptor activity |
|
GO:0004935 |
adrenergic receptor activity |
|
GO:0004937 |
alpha1-adrenergic receptor activity |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006915 |
apoptosis |
|
GO:0006939 |
smooth muscle contraction |
|
GO:0006950 |
response to stress |
|
GO:0007165 |
signal transduction |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007202 |
activation of phospholipase C activity |
|
GO:0007204 |
elevation of cytosolic calcium ion concentration |
|
GO:0007243 |
intracellular protein kinase cascade |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007568 |
aging |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009725 |
response to hormone stimulus |
|
GO:0032229 |
negative regulation of synaptic transmission, GABAergic |
|
GO:0035024 |
negative regulation of Rho protein signal transduction |
|
GO:0042493 |
response to drug |
|
GO:0045760 |
positive regulation of action potential |
|
GO:0045907 |
positive regulation of vasoconstriction |
|
GO:0060402 |
calcium ion transport into cytosol |
|
GO:0060452 |
positive regulation of cardiac muscle contraction |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
|
GO:0090037 |
positive regulation of protein kinase C signaling cascade |
