HuLG000105

Entrez Gene ID

150

Official Gene Symbol

ADRA2A

Synonyms

ADRA2|ADRA2R|ADRAR|ALPHA2AAR|ZNF32

Gene name

adrenergic, alpha-2A-, receptor

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24-q26

Protein products

Alpha-2A adrenergic receptor

DNA-binding protein

DNA-binding protein

DNA-binding protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:281
MIM:104210
Ensembl:ENSG00000150594
HPRD:00078
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

GO annotation

GO:0001819

positive regulation of cytokine production

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0004935

adrenergic receptor activity

GO:0004938

alpha2-adrenergic receptor activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006112

energy reserve metabolic process

GO:0006928

cellular component movement

GO:0007165

signal transduction

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007194

negative regulation of adenylate cyclase activity

GO:0007265

Ras protein signal transduction

GO:0007266

Rho protein signal transduction

GO:0007596

blood coagulation

GO:0008284

positive regulation of cell proliferation

GO:0010700

negative regulation of norepinephrine secretion

GO:0016323

basolateral plasma membrane

GO:0019901

protein kinase binding

GO:0030036

actin cytoskeleton organization

GO:0030335

positive regulation of cell migration

GO:0030818

negative regulation of cAMP biosynthetic process

GO:0031692

alpha-1B adrenergic receptor binding

GO:0031696

alpha-2C adrenergic receptor binding

GO:0031996

thioesterase binding

GO:0032147

activation of protein kinase activity

GO:0032148

activation of protein kinase B activity

GO:0032795

heterotrimeric G-protein binding

GO:0032811

negative regulation of epinephrine secretion

GO:0032870

cellular response to hormone stimulus

GO:0035625

epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway

GO:0042593

glucose homeostasis

GO:0042596

fear response

GO:0042803

protein homodimerization activity

GO:0043235

receptor complex

GO:0043268

positive regulation of potassium ion transport

GO:0043406

positive regulation of MAP kinase activity

GO:0045741

positive regulation of epidermal growth factor receptor activity

GO:0045955

negative regulation of calcium ion-dependent exocytosis

GO:0046676

negative regulation of insulin secretion

GO:0046982

protein heterodimerization activity

GO:0050796

regulation of insulin secretion

GO:0050892

intestinal absorption

GO:0050995

negative regulation of lipid catabolic process

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

GO:0051379

epinephrine binding

GO:0051380

norepinephrine binding

GO:0051927

negative regulation of calcium ion transport via voltage-gated calcium channel activity

GO:0061179

negative regulation of insulin secretion involved in cellular response to glucose stimulus

GO:0071881

inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway

GO:0071882

activation of phospholipase C activity by adrenergic receptor signaling pathway

GO:0071883

activation of MAPK activity by adrenergic receptor signaling pathway

GO:0090303

positive regulation of wound healing