HuLG000106

Entrez Gene ID

151

Official Gene Symbol

ADRA2B

Synonyms

ADRA2L1|ADRA2RL1|ADRARL1|ALPHA2BAR

Gene name

adrenergic, alpha-2B-, receptor

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p13-q13

Known cancer genes

Yes

Protein products

Adrenergic, alpha-2B-, receptor

Alpha-2B adrenergic receptor

Database cross reference

HGNC:282
MIM:104260
Ensembl:ENSG00000222040
HPRD:00086
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

GO annotation

GO:0001525

angiogenesis

GO:0003056

regulation of vascular smooth muscle contraction

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0004935

adrenergic receptor activity

GO:0004938

alpha2-adrenergic receptor activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007267

cell-cell signaling

GO:0007596

blood coagulation

GO:0010700

negative regulation of norepinephrine secretion

GO:0032148

activation of protein kinase B activity

GO:0032811

negative regulation of epinephrine secretion

GO:0035625

epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway

GO:0045666

positive regulation of neuron differentiation

GO:0045777

positive regulation of blood pressure

GO:0051379

epinephrine binding

GO:0070474

positive regulation of uterine smooth muscle contraction

GO:0071883

activation of MAPK activity by adrenergic receptor signaling pathway