Gene basic information
| LiverAtlas Gene ID |
HuLG000109 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ADRB2 |
|
Synonyms |
ADRB2R|ADRBR|B2AR|BAR|BETA2AR |
|
Gene name |
adrenergic, beta-2-, receptor, surface |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5q31-q32 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:286
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002024 |
diet induced thermogenesis |
|
GO:0002025 |
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure |
|
GO:0002032 |
desensitization of G-protein coupled receptor protein signaling pathway by arrestin |
|
GO:0002086 |
diaphragm contraction |
|
GO:0004872 |
receptor activity |
|
GO:0004930 |
G-protein coupled receptor activity |
|
GO:0004935 |
adrenergic receptor activity |
|
GO:0004941 |
beta2-adrenergic receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005634 |
nucleus |
|
GO:0005764 |
lysosome |
|
GO:0005768 |
endosome |
|
GO:0005792 |
microsome |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0005901 |
caveola |
|
GO:0006898 |
receptor-mediated endocytosis |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007171 |
activation of transmembrane receptor protein tyrosine kinase activity |
|
GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
|
GO:0007189 |
activation of adenylate cyclase activity by G-protein signaling pathway |
|
GO:0007190 |
activation of adenylate cyclase activity |
|
GO:0008144 |
drug binding |
|
GO:0008179 |
adenylate cyclase binding |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008333 |
endosome to lysosome transport |
|
GO:0009409 |
response to cold |
|
GO:0010765 |
positive regulation of sodium ion transport |
|
GO:0015459 |
potassium channel regulator activity |
|
GO:0016324 |
apical plasma membrane |
|
GO:0030279 |
negative regulation of ossification |
|
GO:0030424 |
axon |
|
GO:0030501 |
positive regulation of bone mineralization |
|
GO:0031649 |
heat generation |
|
GO:0032809 |
neuronal cell body membrane |
|
GO:0035240 |
dopamine binding |
|
GO:0035255 |
ionotropic glutamate receptor binding |
|
GO:0040015 |
negative regulation of multicellular organism growth |
|
GO:0042383 |
sarcolemma |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043197 |
dendritic spine |
|
GO:0043235 |
receptor complex |
|
GO:0043268 |
positive regulation of potassium ion transport |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0044424 |
intracellular part |
|
GO:0045453 |
bone resorption |
|
GO:0045823 |
positive regulation of heart contraction |
|
GO:0045909 |
positive regulation of vasodilation |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0045986 |
negative regulation of smooth muscle contraction |
|
GO:0048633 |
positive regulation of skeletal muscle tissue growth |
|
GO:0050728 |
negative regulation of inflammatory response |
|
GO:0050873 |
brown fat cell differentiation |
|
GO:0051379 |
epinephrine binding |
|
GO:0051380 |
norepinephrine binding |
|
GO:0051927 |
negative regulation of calcium ion transport via voltage-gated calcium channel activity |
|
GO:0051930 |
regulation of sensory perception of pain |
