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Gene basic information

LiverAtlas Gene ID

HuLG000111

Entrez Gene ID

156

Official Gene Symbol

ADRBK1

Synonyms

BARK1|BETANARK1|FLJ16718|GRK2

Gene name

adrenergic, beta, receptor kinase 1

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13.1

Known cancer genes

Yes

Protein products

Beta-adrenergic receptor kinase 1

Database cross reference

HGNC:289
MIM:109635
Ensembl:ENSG00000173020
HPRD:00182
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0002026

regulation of the force of heart contraction

GO:0002029

desensitization of G-protein coupled receptor protein signaling pathway

GO:0003108

negative regulation of the force of heart contraction by chemical signal

GO:0004672

protein kinase activity

GO:0004703

G-protein coupled receptor kinase activity

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005624

membrane fraction

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0005901

caveola

GO:0006979

response to oxidative stress

GO:0007202

activation of phospholipase C activity

GO:0007213

muscarinic acetylcholine receptor signaling pathway

GO:0007217

tachykinin receptor signaling pathway

GO:0007507

heart development

GO:0007568

aging

GO:0014070

response to organic cyclic compound

GO:0016020

membrane

GO:0016323

basolateral plasma membrane

GO:0016324

apical plasma membrane

GO:0018105

peptidyl-serine phosphorylation

GO:0018107

peptidyl-threonine phosphorylation

GO:0030424

axon

GO:0031694

alpha-2A adrenergic receptor binding

GO:0031755

Edg-2 lysophosphatidic acid receptor binding

GO:0033605

positive regulation of catecholamine secretion

GO:0042542

response to hydrogen peroxide

GO:0042699

follicle-stimulating hormone signaling pathway

GO:0043197

dendritic spine

GO:0043198

dendritic shaft

GO:0045202

synapse

GO:0045988

negative regulation of striated muscle contraction

GO:0047696

beta-adrenergic receptor kinase activity

GO:0048011

nerve growth factor receptor signaling pathway

GO:0060048

cardiac muscle contraction