Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000131

Entrez Gene ID

182

Official Gene Symbol

JAG1

Synonyms

AGS|AHD|AWS|CD339|HJ1|JAGL1|MGC104644

Gene name

jagged 1

Gene Type

protein-coding

Chromosome

20

Genomics Location

20p12.1-p11.23

Known cancer genes

Yes

Protein products

Protein jagged-1

Jagged 1 (Alagille syndrome)

Soluble protein Jagged

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:6188
MIM:601920
Ensembl:ENSG00000101384
HPRD:03562
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0001709

cell fate determination

GO:0002011

morphogenesis of an epithelial sheet

GO:0005112

Notch binding

GO:0005198

structural molecule activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007154

cell communication

GO:0007219

Notch signaling pathway

GO:0007220

Notch receptor processing

GO:0007275

multicellular organismal development

GO:0007399

nervous system development

GO:0008083

growth factor activity

GO:0009887

organ morphogenesis

GO:0016020

membrane

GO:0030097

hemopoiesis

GO:0030216

keratinocyte differentiation

GO:0030334

regulation of cell migration

GO:0032495

response to muramyl dipeptide

GO:0042127

regulation of cell proliferation

GO:0042491

auditory receptor cell differentiation

GO:0045445

myoblast differentiation

GO:0045446

endothelial cell differentiation

GO:0045596

negative regulation of cell differentiation

GO:0045639

positive regulation of myeloid cell differentiation

GO:0045747

positive regulation of Notch signaling pathway

GO:0048839

inner ear development