Gene basic information
| LiverAtlas Gene ID |
HuLG000132 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AGT |
|
Synonyms |
ANHU|FLJ92595|FLJ97926|SERPINA8 |
|
Gene name |
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q42-q43 |
|
Known cancer genes |
Yes |
|
Protein products |
Angiotensinogen (Serpin peptidase inhibitor, clade A, member 8) |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:333
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001543 |
ovarian follicle rupture |
|
GO:0001558 |
regulation of cell growth |
|
GO:0001568 |
blood vessel development |
|
GO:0001819 |
positive regulation of cytokine production |
|
GO:0001822 |
kidney development |
|
GO:0001974 |
blood vessel remodeling |
|
GO:0001998 |
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure |
|
GO:0001999 |
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure |
|
GO:0002016 |
regulation of blood volume by renin-angiotensin |
|
GO:0002018 |
renin-angiotensin regulation of aldosterone production |
|
GO:0002019 |
regulation of renal output by angiotensin |
|
GO:0002034 |
regulation of blood vessel size by renin-angiotensin |
|
GO:0002035 |
brain renin-angiotensin system |
|
GO:0004867 |
serine-type endopeptidase inhibitor activity |
|
GO:0005179 |
hormone activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005625 |
soluble fraction |
|
GO:0006883 |
cellular sodium ion homeostasis |
|
GO:0007160 |
cell-matrix adhesion |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007199 |
G-protein signaling, coupled to cGMP nucleotide second messenger |
|
GO:0007200 |
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger |
|
GO:0007263 |
nitric oxide mediated signal transduction |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007588 |
excretion |
|
GO:0008065 |
establishment of blood-nerve barrier |
|
GO:0008083 |
growth factor activity |
|
GO:0008217 |
regulation of blood pressure |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009409 |
response to cold |
|
GO:0009651 |
response to salt stress |
|
GO:0010535 |
positive regulation of activation of JAK2 kinase activity |
|
GO:0010595 |
positive regulation of endothelial cell migration |
|
GO:0010613 |
positive regulation of cardiac muscle hypertrophy |
|
GO:0010698 |
acetyltransferase activator activity |
|
GO:0010744 |
positive regulation of macrophage derived foam cell differentiation |
|
GO:0010873 |
positive regulation of cholesterol esterification |
|
GO:0010951 |
negative regulation of endopeptidase activity |
|
GO:0014061 |
regulation of norepinephrine secretion |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0014873 |
response to muscle activity involved in regulation of muscle adaptation |
|
GO:0019229 |
regulation of vasoconstriction |
|
GO:0030162 |
regulation of proteolysis |
|
GO:0030198 |
extracellular matrix organization |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0030432 |
peristalsis |
|
GO:0031702 |
type 1 angiotensin receptor binding |
|
GO:0031703 |
type 2 angiotensin receptor binding |
|
GO:0032270 |
positive regulation of cellular protein metabolic process |
|
GO:0033864 |
positive regulation of NAD(P)H oxidase activity |
|
GO:0034374 |
low-density lipoprotein particle remodeling |
|
GO:0040018 |
positive regulation of multicellular organism growth |
|
GO:0042127 |
regulation of cell proliferation |
|
GO:0042445 |
hormone metabolic process |
|
GO:0042756 |
drinking behavior |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043085 |
positive regulation of catalytic activity |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0044444 |
cytoplasmic part |
|
GO:0045723 |
positive regulation of fatty acid biosynthetic process |
|
GO:0045742 |
positive regulation of epidermal growth factor receptor signaling pathway |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0046622 |
positive regulation of organ growth |
|
GO:0048143 |
astrocyte activation |
|
GO:0048146 |
positive regulation of fibroblast proliferation |
|
GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
|
GO:0048659 |
smooth muscle cell proliferation |
|
GO:0050729 |
positive regulation of inflammatory response |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051145 |
smooth muscle cell differentiation |
|
GO:0051387 |
negative regulation of nerve growth factor receptor signaling pathway |
|
GO:0061098 |
positive regulation of protein tyrosine kinase activity |
|
GO:0090190 |
positive regulation of branching involved in ureteric bud morphogenesis |
|
GO:2000379 |
positive regulation of reactive oxygen species metabolic process |
