Gene basic information
| LiverAtlas Gene ID |
HuLG000133 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AGTR1 |
|
Synonyms |
AG2S|AGTR1A|AGTR1B|AT1|AT1B|AT1R|AT2R1|AT2R1A|AT2R1B|HAT1R |
|
Gene name |
angiotensin II receptor, type 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3q24 |
|
Known cancer genes |
Yes |
|
Protein products |
Type-1 angiotensin II receptor |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
|
Database cross reference |
HGNC:336
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001558 |
regulation of cell growth |
|
GO:0001596 |
angiotensin type I receptor activity |
|
GO:0001822 |
kidney development |
|
GO:0002018 |
renin-angiotensin regulation of aldosterone production |
|
GO:0002034 |
regulation of blood vessel size by renin-angiotensin |
|
GO:0003081 |
regulation of systemic arterial blood pressure by renin-angiotensin |
|
GO:0004872 |
receptor activity |
|
GO:0004930 |
G-protein coupled receptor activity |
|
GO:0004945 |
angiotensin type II receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007200 |
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger |
|
GO:0007204 |
elevation of cytosolic calcium ion concentration |
|
GO:0007266 |
Rho protein signal transduction |
|
GO:0010698 |
acetyltransferase activator activity |
|
GO:0010744 |
positive regulation of macrophage derived foam cell differentiation |
|
GO:0010873 |
positive regulation of cholesterol esterification |
|
GO:0016021 |
integral to membrane |
|
GO:0019229 |
regulation of vasoconstriction |
|
GO:0019722 |
calcium-mediated signaling |
|
GO:0031711 |
bradykinin receptor binding |
|
GO:0032270 |
positive regulation of cellular protein metabolic process |
|
GO:0032430 |
positive regulation of phospholipase A2 activity |
|
GO:0033864 |
positive regulation of NAD(P)H oxidase activity |
|
GO:0034374 |
low-density lipoprotein particle remodeling |
|
GO:0042127 |
regulation of cell proliferation |
|
GO:0042312 |
regulation of vasodilation |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0050727 |
regulation of inflammatory response |
|
GO:0050729 |
positive regulation of inflammatory response |
|
GO:0051482 |
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger |
|
GO:0060326 |
cell chemotaxis |
|
GO:2000379 |
positive regulation of reactive oxygen species metabolic process |
