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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000134

Entrez Gene ID

186

Official Gene Symbol

AGTR2

Synonyms

AT2|ATGR2|MRX88

Gene name

angiotensin II receptor, type 2

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xq22-q23

Known cancer genes

Yes

Protein products

Type-2 angiotensin II receptor

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:338
MIM:300034
Ensembl:ENSG00000180772
HPRD:02071
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

 

Ontology annotation

GO ID

GO annotation

GO:0001974

blood vessel remodeling

GO:0001991

regulation of systemic arterial blood pressure by circulatory renin-angiotensin

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0004945

angiotensin type II receptor activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007166

cell surface receptor linked signaling pathway

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007199

G-protein signaling, coupled to cGMP nucleotide second messenger

GO:0007243

intracellular protein kinase cascade

GO:0007263

nitric oxide mediated signal transduction

GO:0007420

brain development

GO:0007610

behavior

GO:0008217

regulation of blood pressure

GO:0009968

negative regulation of signal transduction

GO:0010459

negative regulation of heart rate

GO:0030308

negative regulation of cell growth

GO:0032516

positive regulation of phosphoprotein phosphatase activity

GO:0043065

positive regulation of apoptosis

GO:0043537

negative regulation of blood vessel endothelial cell migration

GO:0045429

positive regulation of nitric oxide biosynthetic process

GO:0045909

positive regulation of vasodilation

GO:0048019

receptor antagonist activity

GO:0051000

positive regulation of nitric-oxide synthase activity

GO:0051387

negative regulation of nerve growth factor receptor signaling pathway