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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000136

Entrez Gene ID

189

Official Gene Symbol

AGXT

Synonyms

AGT|AGT1|AGXT1|PH1|SPAT|SPT|TLH6

Gene name

alanine-glyoxylate aminotransferase

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q37.3

Known cancer genes

Yes

Protein products

Alanine:glyoxylate aminotransferase

Alanine-glyoxylate aminotransferase homolog

Serine--pyruvate aminotransferase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:341
MIM:604285
Ensembl:ENSG00000172482
HPRD:05048
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

BodyMap

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004760

serine-pyruvate transaminase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0005777

peroxisome

GO:0005782

peroxisomal matrix

GO:0006625

protein targeting to peroxisome

GO:0008453

alanine-glyoxylate transaminase activity

GO:0016597

amino acid binding

GO:0016740

transferase activity

GO:0019265

glycine biosynthetic process, by transamination of glyoxylate

GO:0030170

pyridoxal phosphate binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0042803

protein homodimerization activity

GO:0042866

pyruvate biosynthetic process

GO:0046487

glyoxylate metabolic process

GO:0046724

oxalic acid secretion

GO:0051384

response to glucocorticoid stimulus

GO:0051591

response to cAMP