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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000141

Entrez Gene ID

199

Official Gene Symbol

AIF1

Synonyms

AIFN1|IBA1|IRTN1|IRT1

Gene name

allograft inflammatory factor 1

Gene Type

protein-coding

Chromosome

6

Genomics Location

6p21.3

Known cancer genes

Yes

Protein products

Allograft inflammatory factor 1

Serine protease

Allograft inflammatory factor 1 isoform 2

Allograft inflammatory factor 1

Coagulation factor V jinjiang A2 domain

AIF1 protein

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:352
MIM:601833
Ensembl:ENSG00000204472
HPRD:03496
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

 

Ontology annotation

GO ID

GO annotation

GO:0001891

phagocytic cup

GO:0001934

positive regulation of protein phosphorylation

GO:0005509

calcium ion binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005884

actin filament

GO:0005886

plasma membrane

GO:0006950

response to stress

GO:0006954

inflammatory response

GO:0007050

cell cycle arrest

GO:0008285

negative regulation of cell proliferation

GO:0010629

negative regulation of gene expression

GO:0014739

positive regulation of muscle hyperplasia

GO:0030027

lamellipodium

GO:0030335

positive regulation of cell migration

GO:0031668

cellular response to extracellular stimulus

GO:0032587

ruffle membrane

GO:0032870

cellular response to hormone stimulus

GO:0034097

response to cytokine stimulus

GO:0043066

negative regulation of apoptosis

GO:0043204

perikaryon

GO:0045429

positive regulation of nitric oxide biosynthetic process

GO:0048661

positive regulation of smooth muscle cell proliferation

GO:0048678

response to axon injury

GO:0051015

actin filament binding

GO:0051017

actin filament bundle assembly

GO:0051602

response to electrical stimulus

GO:0070887

cellular response to chemical stimulus