HuLG000155

Entrez Gene ID

217

Official Gene Symbol

ALDH2

Synonyms

ALDHNE2|ALDHI|ALDM|MGC1806

Gene name

aldehyde dehydrogenase 2 family (mitochondrial)

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.2

Known cancer genes

Yes

Protein products

Aldehyde dehydrogenase, mitochondrial

Uncharacterized protein

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Alcoholic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:404
MIM:100650
Ensembl:ENSG00000111275
HPRD:00003
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0001889

liver development

GO:0004029

aldehyde dehydrogenase (NAD) activity

GO:0004030

aldehyde dehydrogenase [NAD(P)+] activity

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0005975

carbohydrate metabolic process

GO:0006066

alcohol metabolic process

GO:0006069

ethanol oxidation

GO:0006805

xenobiotic metabolic process

GO:0007268

synaptic transmission

GO:0009055

electron carrier activity

GO:0016491

oxidoreductase activity

GO:0032496

response to lipopolysaccharide

GO:0032570

response to progesterone stimulus

GO:0032870

cellular response to hormone stimulus

GO:0033574

response to testosterone stimulus

GO:0035094

response to nicotine

GO:0042136

neurotransmitter biosynthetic process

GO:0042802

identical protein binding

GO:0055093

response to hyperoxia

GO:0071398

cellular response to fatty acid