HuLG000166

Entrez Gene ID

229

Official Gene Symbol

ALDOB

Synonyms

ALDB|ALDO2

Gene name

aldolase B, fructose-bisphosphate

Gene Type

protein-coding

Chromosome

9

Genomics Location

9q21.3-q22.2

Known cancer genes

Yes

Protein products

Fructose-bisphosphate aldolase B

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Hereditary fructose intolerance

Hepatocellular carcinoma

Database cross reference

HGNC:417
MIM:612724
Ensembl:ENSG00000136872
HPRD:01972
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

GO annotation

GO:0001889

liver development

GO:0004332

fructose-bisphosphate aldolase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005764

lysosome

GO:0005792

microsome

GO:0005815

microtubule organizing center

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0005975

carbohydrate metabolic process

GO:0006000

fructose metabolic process

GO:0006001

fructose catabolic process

GO:0006006

glucose metabolic process

GO:0006094

gluconeogenesis

GO:0006096

glycolysis

GO:0006116

NADH oxidation

GO:0008092

cytoskeletal protein binding

GO:0009743

response to carbohydrate stimulus

GO:0009750

response to fructose stimulus

GO:0010043

response to zinc ion

GO:0014070

response to organic cyclic compound

GO:0016829

lyase activity

GO:0030388

fructose 1,6-bisphosphate metabolic process

GO:0030867

rough endoplasmic reticulum membrane

GO:0030868

smooth endoplasmic reticulum membrane

GO:0031210

phosphatidylcholine binding

GO:0031668

cellular response to extracellular stimulus

GO:0032781

positive regulation of ATPase activity

GO:0032869

cellular response to insulin stimulus

GO:0034451

centriolar satellite

GO:0042493

response to drug

GO:0042594

response to starvation

GO:0042802

identical protein binding

GO:0043200

response to amino acid stimulus

GO:0043434

response to peptide hormone stimulus

GO:0046688

response to copper ion

GO:0048471

perinuclear region of cytoplasm

GO:0051117

ATPase binding

GO:0051384

response to glucocorticoid stimulus

GO:0051591

response to cAMP

GO:0051789

response to protein stimulus

GO:0070061

fructose binding

GO:0070072

vacuolar proton-transporting V-type ATPase complex assembly

GO:0070741

response to interleukin-6