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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000168

Entrez Gene ID

231

Official Gene Symbol

AKR1B1

Synonyms

ADR|ALDR1|ALR2|AR|MGC1804

Gene name

aldo-keto reductase family 1, member B1 (aldose reductase)

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q35

Known cancer genes

Yes

Protein products

Aldose reductase

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:381
MIM:103880
Ensembl:ENSG00000085662
HPRD:00071
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004032

alditol:NADP+ 1-oxidoreductase activity

GO:0004033

aldo-keto reductase (NADP) activity

GO:0005515

protein binding

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005975

carbohydrate metabolic process

GO:0006700

C21-steroid hormone biosynthetic process

GO:0006950

response to stress

GO:0008202

steroid metabolic process

GO:0009055

electron carrier activity

GO:0016491

oxidoreductase activity

GO:0042446

hormone biosynthetic process