Gene basic information
LiverAtlas Gene ID |
HuLG000169 |
Entrez Gene ID |
|
Official Gene Symbol |
ALK |
Synonyms |
CD246|NBLST3 |
Gene name |
anaplastic lymphoma receptor tyrosine kinase |
Gene Type |
protein-coding |
Chromosome |
2 |
Genomics Location |
2p23 |
Known cancer genes |
Yes |
Protein products |
Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor |
Related liver disease name |
|
Database cross reference |
HGNC:427
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
GO:0004872 |
receptor activity |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005887 |
integral to plasma membrane |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
GO:0016020 |
membrane |
GO:0016310 |
phosphorylation |
GO:0046777 |
protein autophosphorylation |